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GlycoFlux™ Human SIGLEC9 Overexpression A549 Cell Line

CAT#: GLJF-0925-JF910

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Overview Specification Target Information Related Products
Overview
Description
GlycoFlux™ human SIGLEC9 overexpression A549 cell line is a stable epithelial system expressing SIGLEC9, a sialic acid- and monosaccharide-binding lectin with predicted adhesion activity and inhibitory roles in inflammation and phagocytosis. Localized to the plasma membrane, SIGLEC9 functions as a checkpoint receptor in innate immunity. This line supports research into glycan-mediated adhesion, pathogen recognition, and immune tolerance.
Product Type
Overexpression Cell Lines
Species
Human
Cell Morphology
Epithelial-like, adherent
Passage Ratio
1:3~1:6
Cell Line
A549
Primary Disease
Non-small cell lung cancer
Lineage
Lung
Lineage Subtype
Non-small cell lung cancer
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
qPCR, Sanger Sequencing
Culture Medium
F-12K & FBS & Penicillin/Streptomycin
Application
Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays.
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
SIGLEC9
Full Name
Sialic Acid Binding Ig Like Lectin 9
Alternative Name
CD329, CDw329, FOAP-9, siglec-9, OBBP-LIKE, Sialic Acid Binding Ig Like Lectin
Location
19q13.3-q13.4
Gene ID
27180
Summary
Predicted to enable monosaccharide binding activity and sialic acid binding activity. Predicted to be involved in cell adhesion. Predicted to act upstream of or within negative regulation of inflammatory response and negative regulation of phagocytosis, engulfment. Predicted to be located in external side of plasma membrane. Predicted to be active in plasma membrane.
For Research Use Only.
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