Recombinant Human ACAN Protein, Glycoengineered Mannose-5 Pichia pastoris

Recombinant human ACAN protein (NP_001126.3) is produced in Glycoengineered Mannose-5 Pichia pastoris. This expression system is used for the production of glycoproteins and antibodies with a mannose-5 structure at N-linked sites.

Glycoengineered Mannose-5 Pichia pastoris

Human

His-tag, FC-tag

>90%, determined by SDS-PAGE.

Regular batch

None

ACAN

Aggrecan core protein

This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene.

Cartilage-specific proteoglycan core protein; CSPCP; Chondroitin sulfate proteoglycan core protein 1; Chondroitin sulfate proteoglycan 1 [Cleaved into: Aggrecan core protein 2]; ACAN; AGC1; CSPG1; MSK16