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Recombinant Human IGF2 protein (NP_000603.1) is produced in Fuco-Adjusted Human Cell Line. This expression system is used for the production of glycoproteins and antibodies with different fucosylation degrees.
This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome.