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DiC8 phosphatidylinositol 3,4-bisphosphate is a chemically synthesized, highly purified lipid. The native phosphatidylinositol 3,4-bisphosphate (PI(3,4)P2) molecule is generated inside active cells by the catalytic action of phosphatidylinositol 3-kinases (PI3Ks) and various lipid phosphatases. This lipid is critical for cellular signaling, as it engages with the pleckstrin homology (PH) domain of the AKT/PKB protein to promote cell viability.