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Recombinant Rabies virus (RABV) (strain CVS-11) Glycoprotein G (G) (20-459 aa) [10xHis-SUMO-tag and Myc-tag], E. coli (CAT#: GPX04-360J)

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1 mg
500 μg
100 μg

Product Overview Recombinant Rabies virus (RABV) (strain CVS-11) Glycoprotein G (20-459 aa) was expressed in E. coli with a 10xHis-SUMO-tag at the N-terminus and Myc-tag at the C-terminus. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, and IP.
Biological Activity Determined by its binding ability in a functional ELISA.
Source E. coli
Species Rabies virus (RABV) (strain CVS-11)
Fragment 20-459 aa
Sequence KFPIYTIPDKLGPWSPIDIHHLSCPNNLVVEDEGCTNLSEFSYMELKVGYISAIKVNGFTCTGVVTEAETYTNFVGYVTTTFKRKHFRPTPDACRAAYNWKMAGDPRYEESLHNPYPDYHWLRTVRTTKESLIIISPSVTDLDPYDKSLHSRVFPGGKCSGITVSSTYCSTNHDYTIWMPENPRPRTPCDIFTNSRGKRASKGNKTCGFVDERGLYKSLKGACRLKLCGVLGLRLMDGTWVAMQTSDETKWCPPDQLVNLHDFRSDEIEHLVVEELVKKREECLDALESIMTTKSVSFRRLSHLRKLVPGFGKAYTIFNKTLMEADAHYKSVRTWNEIIPSKGCLKVGGRCHPHVNGVFFNGIILGPDGHVLIPEMQSSLLQQHMELLKSSVIPLMHPLADPSTVFKEGDEAEDFVEVHLPDVYKQISGVDLGLPNWGKY
Tag 10xHis-SUMO-tag at the N-terminus and Myc-tag at the C-terminus
Predicted MW 69.7 kDa
Purity >90%, determined by SDS-PAGE.
Conjugation Unconjugated
Target G
Full Name Glycoprotein G
Uniprot ID O92284
Background Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells .
Alternate Names Glycoprotein G
For Research Use Only.
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