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GlycoErase™ SIGLEC14 Knockout CHO-K1 Cell Line

CAT#: GLJF-0825-JF863

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Overview Specification Target Information Related Products
Overview
Description
GlycoErase™ SIGLEC14 knockout CHO-K1 cell line is a CHO-K1 model with SIGLEC14 expression removed. SIGLEC14 is predicted to mediate sialic acid binding and cell adhesion, and to localize to granule membranes and the plasma membrane. The knockout provides a tool to examine adhesion biology, innate immune functions, and membrane receptor activity, with applications in glycobiology, immunology, and drug discovery.
Product Type
KO Cell Lines
Species
Hamster
Cell Morphology
Epithelial, adherent
Passage Ratio
1:3~1:5
Cell Line
CHO-K1
Lineage
Chinese hamster ovary
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Culture Medium
FBS & Penicillin/Streptomycin & Proline & RPMI
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
SIGLEC14
Full Name
Sialic Acid Binding Ig Like Lectin 14
Alternative Name
Sialic Acid Binding Ig Like Lectin
Summary
This protein is predicted to bind sialic acid and is involved in cell adhesion. It is predicted to be located in ficolin-1-rich granule membranes and active within the plasma membrane.
For Research Use Only.
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