GlycoErase™ SIGLEC16 Knockout CHO-K1 Cell Line

GlycoErase™ SIGLEC16 knockout CHO-K1 cell line is a CHO-K1 cell line where SIGLEC16 expression has been deleted. SIGLEC16 acts as a sialic acid-binding receptor involved in antibacterial defense responses and interleukin-6 regulation, and is localized to the plasma membrane. The knockout CHO-K1 system supports studies of host-pathogen interactions, cytokine signaling, and innate immune activation, with applications in infectious disease models, inflammation research, and therapeutic development.

KO Cell Lines

Hamster

Epithelial, adherent

1:3~1:5

CHO-K1

Chinese hamster ovary

>90%

The sterility test indicated an absence of microbial growth.

STR identification

Negative

Negative for HIV, HBV and HCV.

We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.

PCR, Sanger Sequencing

FBS & Penicillin/Streptomycin & Proline & RPMI

Functional assay

1 M cells/vial*2

Frozen

Dry ice

Made to order

Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.

This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

SIGLEC16

Sialic Acid Binding Ig Like Lectin 16

SIGLECP16, Siglec-P16, Sialic Acid Binding Ig Like Lectin

This protein is predicted to bind sialic acid and is involved in the positive regulation of defense responses to bacteria and the production of interleukin-6. It is predicted to be located in the membrane and active in the plasma membrane.