Recombinant Human herpesvirus 3 (HHV-3) (strain Oka vaccine) Envelope glycoprotein I (21-354 aa), E. coli

Recombinant Human herpesvirus 3 (HHV-3) (strain Oka vaccine) Envelope glycoprotein I (21-354 aa) was produced using E. coli cell-free expression system with a His-tag or Tag free. Measured by its binding ability in a functional ELISA.

Measured by its binding ability in a functional ELISA.

E. coli cell-free expression system

Human herpesvirus 3 (HHV-3)(strain Oka vaccine)

21-354 aa

His-tag or Tag free

>90%, determined by SDS-PAGE.

Unconjugated

gI

Envelope glycoprotein I

In epithelial cells, the heterodimer gE/gI is required for the cell-to-cell spread of the virus, by sorting nascent virions to cell junctions. Once the virus reaches the cell junctions, virus particles can spread to adjacent cells extremely rapidly through interactions with cellular receptors that accumulate at these junctions. Implicated in basolateral spread in polarized cells. In neuronal cells, gE/gI is essential for the anterograde spread of the infection throughout the host nervous system. Together with US12, the heterodimer gE/gI is involved in the sorting and transport of viral structural components toward axon tips.

Envelope glycoprotein I