Recombinant Human herpesvirus 6B Envelope glycoprotein L (gL) (19-250 aa), Baculovirus

Recombinant Human herpesvirus 6B (strain Z29) (HHV-6 variant B) Envelope glycoprotein L (19-250 aa) was expressed in Baculovirus with a His-tag or Tag free. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, and IP.

Determined by its binding ability in a functional ELISA.

Baculovirus

Human herpesvirus 6B (strain Z29) (HHV-6 variant B)

19-250 aa

MP LFDHNSFYFE KLDDCIAAVI NCTRSEVPLL LEPIYQPPVY NEDVMSILLK PPTKKKPFSR IMVTNEFLSD FLLLQDNPEQ LRTLFALIGD PESRDNWLNF FNGFQTCSPS VGITTCISDN CRKYLPERIT YVNNFFVDNI AGLEFNISEN TDSFYSNIGF LLYLENPATG ITKIIRFPFN SLTLFDTILN CLKYFHLKTG VEFDLLKQME AYNSKLPFRS SRPTILIRNT

His-tag or Tag free

>90%, determined by SDS-PAGE.

Unconjugated

gL

Envelope glycoprotein L

The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Acts as a functional inhibitor of gH and maintains gH in an inhibited form. Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH.

Envelope glycoprotein L; gL