Recombinant Simian varicella virus Envelope glycoprotein I (21-353 aa), E. coli

Recombinant Simian varicella virus Envelope glycoprotein I (21-353 aa) was produced using E. coli cell-free expression system with a His-tag or Tag free. Measured by its binding ability in a functional ELISA.

Measured by its binding ability in a functional ELISA.

E. coli cell-free expression system

Simian varicella virus

21-353 aa

His-tag or Tag free

>90%, determined by SDS-PAGE.

Unconjugated

gI

Envelope glycoprotein I

In epithelial cells, the heterodimer gE/gI is required for the cell-to-cell spread of the virus, by sorting nascent virions to cell junctions. Once the virus reaches the cell junctions, virus particles can spread to adjacent cells extremely rapidly through interactions with cellular receptors that accumulate at these junctions. Implicated in basolateral spread in polarized cells. In neuronal cells, gE/gI is essential for the anterograde spread of the infection throughout the host nervous system.

Envelope glycoprotein I