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| Size | Qty | Add To Basket |
|---|---|---|
| 1 M cells/vial*2 |
| Description | GlycoFlux™ human SIGLEC7 overexpression CHO-K1 cell line is a stable cell line engineered to overexpress SIGLEC7, a predicted sialic acid-binding receptor involved in cell adhesion at the plasma membrane. This system provides a model for analyzing lectin-mediated adhesion, immune glycosylation signaling, and glycan recognition across non-human cell systems. |
| Product Type | Overexpression Cell Lines |
| Species | Hamster |
| Cell Morphology | Epithelial, adherent |
| Passage Ratio | 1:3~1:5 |
| Cell Line | CHO-K1 |
| Lineage | Chinese hamster ovary |
| Cell Viability | >90% |
| Sterility Test | The sterility test indicated an absence of microbial growth. |
| Identity Test | STR identification |
| Mycoplasma Test | Negative |
| Virus Test | Negative for HIV, HBV and HCV. |
| Genetic Stability Testing | We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements. |
| Validation | qPCR, Sanger Sequencing |
| Culture Medium | FBS & Penicillin/Streptomycin & Proline & DMEM |
| Application | Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays. |
| Size | 1 M cells/vial*2 |
| Product Format | Frozen |
| Shipping | Dry ice |
| Availability Status | Made to order |
| Handling Notes | Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to. |
| Product Disclaimer | This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous. |
| Target | SIGLEC7 |
| Full Name | Sialic Acid Binding Ig Like Lectin 7 |
| Alternative Name | p75, QA79, AIRM1, CD328, AIRM-1, CDw328, D-siglec, SIGLEC-7, SIGLECP2, SIGLEC19P, p75/AIRM1, Sialic Acid Binding Ig Like Lectin |
| Location | 19q13.41 |
| Gene ID | 27036 |
| Summary | The encoded protein is predicted to bind sialic acid and participate in cell adhesion. It is expected to be located in the membrane and to function actively within the plasma membrane. |