DMEM Low Glucose for SILAC

DMEM low glucose for SILAC is a specialized cell culture medium designed to facilitate stable isotope labeling by amino acids in cell culture (SILAC) experiments, particularly in scenarios where glucose levels need to be controlled or minimized. This modified Dulbecco's Modified Eagle Medium (DMEM) is formulated with a reduced glucose concentration, alongside the absence of specific amino acids like lysine and arginine, enabling researchers to precisely introduce isotopically labeled versions. By culturing cells in this low-glucose SILAC medium, researchers can achieve accurate and reliable quantification of protein expression changes under conditions where glucose metabolism is a critical factor.

Low glucose DMEM for SILAC; SILAC DMEM with low glucose; SILAC-compatible low glucose DMEM; Low-glucose DMEM for stable isotope labeling

Liquid

Store at 2-8°C for long term storage.

DMEM low glucose for SILAC is primarily used in quantitative proteomics to analyze protein expression and turnover by mass spectrometry. By incorporating heavy isotopes into proteins during cell growth, scientists can accurately quantify differences in protein abundance between samples, facilitating advanced research in cell biology, molecular biology, and biochemistry.