Recombinant Human CSF2 Protein, Fuco-Adjusted Human Cell Line (CAT#: GLJF-0922-JF1005)

Product Overview	Recombinant Human CSF2 protein (NP_000749.2) is produced in Fuco-Adjusted Human Cell Line. This expression system is used for the production of glycoproteins and antibodies with different fucosylation degrees.
Source	Fuco-Adjusted Human Cell Lines
Species	Human
Tag	His-Tag, FC-Tag or other Tags as required.
Purity	>90%
Endotoxin Level	Regular batch
Conjugation	None

Target	CSF2
Full Name	Granulocyte-macrophage colony-stimulating factor
Gene ID	1437
Uniprot ID	P04141
Accession Number	NP_000749.2
Background	The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. This gene plays a role in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been detected in SARS-CoV-2 infected patients that develop acute respiratory distress syndrome.
Alternate Names	GMCSF