Creative Biolabs is professional in building a wide variety of neurological disease models using non-human primates, especially cerebral stroke NHP models. Our company gathers the top scientists and the most advanced experimental platforms to provide the most comprehensive and satisfactory service for our global clients.

Neuroscience (or neurobiology) is a multidisciplinary branch of biology, that focus on the study of brain and nervous system, including molecular neuroscience, cellular neuroscience, cognitive neuroscience, psychophysics, computational modeling and diseases of the nervous system, etc. Studies on the nervous system excavate considerable information on the various neurological disorder (e.g. Parkinson's disease, spinal cord injury, middle cerebral artery occlusion, and cerebral infarction) and help to establish novel treatments and drugs.

Advantages of non-human primates (NHPs)

Non-human primates (NHPs) are widely used in the study of human neurological diseases because they may be the only animals with the closest anatomy, pathophysiology characteristics, disease onset/progression mode to that of humans. Sometimes only non-human primates can respond to or be affected by a potential vaccine or medicine as human does.

Cerebral Stroke Model

What is cerebral stroke?

A stroke is cell death caused by poor blood supply to the brain. It will result in part of the brain not functioning properly. Stroke can be divided into two types: ischemic due to lack of blood flow and hemorrhagic due to bleeding. The focal cerebral ischemic model of stroke is commonly used to evaluate ischemic injury of the brain. Signs and symptoms of a stroke may include:

  • Trouble with speaking and understanding
  • Trouble with walking
  • Trouble with seeing in one or both eyes
  • Paralysis or numbness of the face, arm or leg
  • Headache

Cerebral Stroke Model

Cerebral stroke model provided by Creative Biolabs

Cerebral stroke models can be established by the latest microneurosurgery technique. We adopt micro catheter embolization or blood vessel clamping method through-pterion, orbital or supraorbital operation to build the cerebral stroke model. The comprehensive testing package can be provided including:

  • A standard neurological deficit score: sensory system defects, conscious state, motor system, skeletal muscle coordination
  • MRI imaging for judging the state and calculating the relative infarct volume percentage
  • Physiological parameters: BP, BBT, pH, pCO2, pO2, sO2, and GLU

Creative Biolabs is a senior expert in the field of NHP models establishment. Multiple models are available on our website (e.g. renal disease, cardiovascular and metabolic disorders, liver disease, urogenital disease, and immune disease). Please feel free to contact us for further discussions.

For Research Use Only.



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