As a leading company in pharmacology industry, Creative Biolabs has successfully provided a series of in vivo PK studies for worldwide customers. Importantly, now we are capable of providing PK/bioanalysis services in the most high-quality and cost-effective way. Our professional scientists with well-equipped bioanalytical laboratories are more than happy to support the development of our client’s new drug programs.

Introduction of PK/Bioanalysis for the Samples

Quantitation of drugs and their metabolites in human and animal tissues is an important aspect of drug discovery and development. In the drug-discovery setting, tissue analyses are needed as part of target organ penetration studies for in vivo pharmacological assessments. In particular, drug concentrations in tissues of preclinical species can be used for human dosimetry prediction and the primary or secondary endpoints for pharmacological effect and safety monitoring. Therefore, bioanalysis of drugs and their metabolites in samples can play an important role in understanding the pharmacological and toxicological properties of new drug candidates.

Workflow of samples analysis. Fig.1 Workflow of samples analysis.

Our Capabilities

Creative Biolabs is a global leader in clinical and nonclinical bioanalysis. During the past years, our bioanalysis team has developed a series of samples analysis services, including proprietary method development, validation, method transfer, high throughput sample analysis and pharmacokinetic and toxicokinetic support, combined with advanced LC-MS/MS and GC-MS/MS technologies. With extensive experience, our comprehensive service can be performed on both small molecules and large molecules, such as peptides, vaccines, proteins, antibody-drug conjugates, biosimilars, and monoclonal antibodies. In addition, our experienced scientists are able to measure drug and metabolite concentrations for multiple samples, including but not limited to:

  • Plasma/Serum
  • Whole blood
  • Dried blood spots
  • Translucent Matrices (Tears, Cerebrospinal fluid, Synovial, Urine, Aqueous, etc.)
  • Tissues (Tumor, Arterial, Kidney, Tendon, Lung, Skin, etc.)

Features of Our Services

  • Personalized: Both standard and custom-built services to meet our client’s requirements
  • Comprehensive: Full-scale samples bioanalysis services to support in vivo PK studies
  • Quickly: Short duration with advanced technologies
  • Cost-effective: Competitive price with the best quality

Creative Biolabs is committed to being your good partner in new drug discovery. With state-of-the-art technology, our professional staffs will offer you trustworthy expert solutions to meet your unique bioanalytical needs. And our scientists and regulatory experts will work closely with you to provide a personalized and comprehensive service to help you gain marketplace advantage.

In addition to samples bioanalysis services, we also provide other in vivo PK study services listed below to meet every client’s requirements.

For more details and information, please feel free to contact us and get a quote.

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