PathSpecific™ AXL Cell-based Phosphorylation Assay (CAT#: ZL-1122-LX294)
| Overview | |
|---|---|
| Short Name | AXL Cell-based Phosphorylation Assay |
| Assay Overview | Creative Biolabs provides several specific target assays for the investigation of test articles focus the specific pathway. This assay is applied for compound screening and profiling in intact cells and will be customized according to the client's specific requirements. Please contact our scientists for assay development and custom-tailored screening details. |
| Assay type | Phosphorylation Assay |
| Assay Properties | |
|---|---|
| Short Description | For compound screening and profiling in intact cells |
| Substrates/Cell Line | Mouse Embryonic Fibroblasts (MEF) |
| Target Expression | Transfected |
| Assay subtype | Cell-based Phosphorylation Assay |
| Assay format | 96-wells format |
| Target | |
|---|---|
| Target | AXL |
| Synonyms | EC; UFO |
| Target Species | Human |
| Target Description | AXL is a receptor tyrosine kinase with a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. AXL stimulation has been described to drive Cell-based proliferation and the protein growth arrest-specific gene-6 (GAS6) has been found to be a ligand. Dysregulation of AXL and its ligand GAS6 is implicated in the pathogenesis of several human cancers. |
For Research Use Only.
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