| Overview | |
|---|---|
| Description | The kit is used to quantitatively measure the activity of Human Angiotensin-Converting Enzyme 2 (ACE2) in biological samples. |
| Features | Ready-used for protease assay |
| Applications | Kit is used to study the ACE2 protease in biological samples. |
| Application Notes | The kit is effective for evaluating the enzymatic activity of both native and purified ACE2. |
| Molecular Mechanism of Action | The kit operates on the principle of ACE2's ability to cleave a synthetically created MCA-based peptide substrate, resulting in the release of a freely floating fluorophore. The amount of fluorophore released depends on the ACE2 activity and can be measured via fluorescence, making it possible to quantify ACE2's enzymatic activity in biological samples. |
| Assay Measures | Fluorogenic-based detection |
| Research Areas | Kinase Drug Discovery; Signal Pathway; |
| Specification | |
|---|---|
| Size | 100 tests |
| Components | The kit is supplied with as assay kit including ACE2 assay buffer, ACE2 dilution buffer, ACE2 inhibitor (22 mM), ACE2 lysis buffer, ACE2 positive control, ACE2 substrate, and MCA-standard (1 mM). |
| Target | ACE2 |
| Sensitivity | 400 µU |
| Format | Supplied with fluorescent assay kit. |
| Storage | Store at -20°C |
| Handling | Please store the kit according to the storage instructions in the kit's manual upon receipt. |
| Shipping | Dry ice |
| Regulatory Status | RUO |
For Research Use Only.
