| Overview | |
|---|---|
| Description | The kit is used to quantitatively assess Factor XIa activity in human plasma, serum, and cell culture supernatant. |
| Features | Ready-used for protease assay |
| Applications | Kit is used to study the Factor XIa protease in biological samples. |
| Application Notes | This kit is convenient for use and able to detect Factor XIa at levels as low as 1 mPEU from both plasma and purified protein samples. |
| Molecular Mechanism of Action | The kit measures the activity of factor XIa by monitoring its ability to cleave a synthetic substrate and release a colored product, p-Nitroaniline (pNA). The amount of pNA can be quantitatively measured using a colorimetric assay at the wavelength of 405 nm. |
| Assay Measures | Colorimetric-based detection |
| Research Areas | Kinase Drug Discovery; Signal Pathway; |
| Specification | |
|---|---|
| Size | 100 tests |
| Components | The kit is supplied with an assay kit including FXIa activator, FXIa assay buffer, FXIa substrate, human Factor Xia, inhibitor 1 & 2, and pNA standard (0.1 M). |
| Target | Factor XIa |
| Format | Supplied with colorimetric assay kit. |
| Storage | Store at -20°C |
| Handling | Please store the kit according to the storage instructions in the kit's manual upon receipt. |
| Shipping | Ice packs |
| Regulatory Status | RUO |
For Research Use Only.
