Gene Knockout

As a leading provider of drug discovery services, Creative Biolabs can help you screen and validate potential targets by using several gene manipulation methods related to genome editing and gene silencing. With over decade of experience and the state-of-the-art drug discovery platforms, we can totally meet your project requirements and budgets in the gene knockout services.

Gene knockout is a genetic technique which makes one or several genes from an organism inoperative. Gene knockout also refers to the gene that is knocked out or the organism that carries the knock-out.gene. Knockout organisms are used to study the gene function, usually by investigating the deficiency effect of the gene. Researchers figure out the differences between the knockout organism and normal individuals.

Creative Biolabs offers a range of gene manipulation solutions to cater to your needs. We perform complete toolset comprising trusted solutions for every step of gene manipulation. The optimized, validated technology systems are designed to minimize and eliminate the trial-and-error phase and help you get answers faster with fewer errors. Scientists in our laboratory have developed FLP-mediated, site-specific gene knockout platforms, including:

• CRISPR/Cas9 System Screening
• Homologous Recombination
• Transcription Activator-like Effector Nuclease Service

All these platforms enable us to identify the targets with better efficacy. Key features of our platform including:

• Highly optimized for general use. We can knockout any gene fewer than 20 kb in size.
• High-quality. Our seamless technology can tailor accurate, high-quality targets and perform permanent gene disruption.
• Fast delivery. Our simple, streamlined protocol can deliver knockout constructs as quickly as 3 days.
• High success rate. The success rate has been kept over 95%.
• Minimal screening to isolate mutants.

Table 1 Comparison of the Gene Editing Methods

Our gene knockout services can be tailor-designed to meet your specific needs and it is fast, reliable, and affordable. If you are interested in using our gene knockout services to support your target validation and identification in drug discovery program, please feel free to contact us for more details.

For Research Use Only.