3-WP, Antimicrobial Peptide (AMP) (CAT#: BMWJ-0826-WJ651)
3-WP is a linear 20-peptide with a C-terminal amidation modification. 3-WP acts on lipoteichoic acid (LTA) and disrupts cell wall permeability, induces intracellular reactive oxygen species (ROS) accumulation in a dose-dependent manner, and simultaneously inhibits respiratory chain dehydrogenase activity and intracellular ATP synthesis, thereby interfering with bacterial energy metabolism and exerting Bacterial antibacterial effects. The combination of 3-WP and Melittin (HY-P0233) exerts synergistic antibacterial effects against Gram-positive bacteria, reduces the required dosage of Melittin, and thus improves the cell selectivity of Melittin. 3-WP can serve as a peptide adjuvant for Melittin in food storage scenarios. 3-WP can be used in the research of foodborne diseases caused by methicillin-resistant Staphylococcus aureus.
| Overview | |
|---|---|
| Synonyms | 3-WP; 3WP; Tryptophan-rich peptide |
| Source | Synthetic |
| Activity | Gram-positive bacteria; Gram-negative bacteria; Fungi; Virus; Cancer cells; Biofilm |
| Physical State | Powder |
| Purity | >98% |
| Storage | The power can be stored at 4°C for 2 years or at -20°C for 3 years. |
For Research Use Only.
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