Glucocorticoid Receptor Pathway-GAL4 Reporter Kit (CAT#: ZL-1123-WR7)

Overview
DescriptionThe kit comprises a transfection-ready expression vector for the glucocorticoid receptor ligand binding domain and a negative control vector. This fusion construct activates firefly luciferase expression under the control of a multimerized GAL4 upstream activation sequence (UAS).
FeaturesReady-used for cell signaling pathway assay.
ApplicationsThe Glucocorticoid Receptor Pathway Reporter Kit is designed for monitoring the activity of the glucocorticoid signaling pathway in cultured cells.
Application Notes• Monitor PI3K/Akt signaling pathway activity and FOXO transcriptional activity.
• Screen for PI3K/AKT signaling pathway compound activity.
• Study effects of RNAi or gene overexpression on the activity of the PI3K/AKT pathway.
Research AreasDrug Discovery; Immunology; Oncology
Specification
Size500 reactions
ComponentsReporter: GAL4/UAS luciferase reporter vector & Renilla luciferase vector
Negative Control Reporter: Non-inducible luciferase vector & Renilla luciferase vector
TargetGlucocorticoid Receptor
FormatSupplied with reporter vector group and negative control vector group.
StorageStore kit components at -20°C.
HandlingPlease place the product at proper storage condition once received.
ShippingIce packs
Regulatory StatusRUO

For Research Use Only.

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