Gramicidin A, Antimicrobial Peptide (AMP) (CAT#: BMWJ-0826-WJ7)
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Gramicidin A is a peptide component of gramicidin, an antibiotic mixture originally isolated from B. brevis. Gramicidin A is a highly hydrophobic channel-forming ionophore that forms channels in model membranes that are permeable to monovalent cations. Gramicidin A induces degradation of hypoxia inducible factor 1 α (HIF-1α).
| Overview | |
|---|---|
| Synonyms | Gramicidin A; Gramicidin A1 |
| Source | Bacteria |
| CAS | 11029-61-1 |
| Molecular Formula | C99H140N20O17 |
| Molecular Weight | 1882.29 |
| Sequence | {For}-Val-Gly-Ala-{D-Leu}-Ala-{D-Val}-Val-{D-Val}-Trp-{D-Leu}-Trp-{D-Leu}-Trp-{D-Leu}- Trp-{NHCH2CH2OH} |
| Activity | Gram-positive bacteria; Gram-negative bacteria; Ion channel; Pore formation; Valinomycin-like |
| Physical State | Powder |
| Purity | >98% |
| Storage | The power can be stored at 4°C for 2 years or at -20°C for 3 years. |
For Research Use Only.
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