Human α-defensin 5, Antimicrobial Peptide (AMP) (CAT#: BMWJ-0826-WJ443)
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Human α-defensin 5 is an antiviral peptide. Human α-defensin 5 blocks infection of non-enveloped viruses, including AdV, HPV, and polyomaviruses (IC50: 0.6-1.25 μM for HPV16). Human α-defensin 5 can bind to the viral capsid and blocks escape of the virus from the endosome. Human α-defensin 5 increases HIV binding to the cell surface. Human α-defensin 5 also has parasiticidal activity.
| Overview | |
|---|---|
| Synonyms | Human α-defensin 5; HD-5; DEFA5 |
| Source | Human |
| Sequence | Ala-Thr-Cys-Tyr-Cys-Arg-Thr-Gly-Arg-Cys-Ala-Thr-Arg-Glu-Ser-Leu-Ser-Gly-Val-Cys-Glu -Ile-Ser-Gly-Arg-Leu-Tyr-Arg-Leu-Cys-Cys-Arg (Disulfide bridge:Cys3-Cys31,Cys5-Cys2 0,Cys10-Cys30) |
| Sequence Shortening | ATCYCRTGRCATRESLSGVCEISGRLYRLCCR (Disulfide bridge:Cys3-Cys31,Cys5-Cys20,Cy s10-Cys30) |
| Activity | Gram-positive bacteria; Gram-negative bacteria; Fungi; Virus; Cancer; Human |
| Physical State | Powder |
| Purity | >98% |
| Storage | The power can be stored at 4°C for 2 years or at -20°C for 3 years. |
For Research Use Only.
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