Nrf2 Antioxidant Pathway-ARE Reporter Kit (CAT#: ZL-1123-WR2)

Overview
DescriptionThe kit contains a transfection-ready ARE luciferase reporter vector and a negative control vector. The reporter vector includes a firefly luciferase gene under the control of multimerized ARE-responsive elements located upstream of a minimal promoter.
FeaturesReady-used for cell signaling pathway assay.
ApplicationsKit is used to study the Nrf2 antioxidant pathway in cultured cells.
Application Notes• Monitor Nrf2 antioxidant response pathway activity.
• Screen for activators or inhibitors of the Nrf2 antioxidant response pathway.
• Study effects of RNAi or gene overexpression on the activity of the Nrf2 pathway.
Research AreasDrug Discovery; Immunology; Oncology
Specification
Size500 reactions
ComponentsReporter: ARE luciferase reporter vector & Renilla luciferase vector
Negative Control Reporter: Non-inducible luciferase vector & Renilla luciferase vector
TargetNrf2
FormatSupplied with reporter vector group and negative control vector group.
StorageStore kit components at -20°C.
HandlingPlease place the product at proper storage condition once received.
ShippingIce packs
Regulatory StatusRUO

For Research Use Only.

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