PathSpecific™ A20/TNFAIP3 Deubiquitination Assay Kit-Fluorogenic (CAT#: ZL-0424-WR49)
| Overview | |
|---|---|
| Description | This kit is designed to measure A20 activity for screening and profiling applications, in a homogeneous assay with no time-consuming washing steps. |
| Features | Ready-used for deubiquitination assay |
| Applications | Useful for examining enzyme kinetics and HTS applications. |
| Assay Measures | Fluorogenic |
| Research Areas | Kinase Drug Discovery; Signal Pathway |
| Specification | |
|---|---|
| Size | 96 tests |
| Components | This kit includes purified A20 protein, Ubiquitin-AMC, and A20 assay buffer for 100 enzyme reactions. |
| Target | A20/TNFAIP3 |
| Target/Description | A20, also known as TNFAIP3, is a crucial protein involved in regulating NF-kB activation. Initially discovered in human umbilical vein endothelial cells, this protein has since been detected in various cell types. A20's significance extends to its involvement in autoimmune and autoinflammatory conditions, notably rheumatoid arthritis. Additionally, A20 contributes to modulating cytokine-induced signaling pathways. |
| Format | Fluorometric assay kit. |
| Storage | Store at the appropriate temperature as directed. |
| Handling | Please handle the product at appropriate storage condition once received. |
| Shipping | Dry ice |
| Regulatory Status | RUO |
For Research Use Only.
Online Inquiry