PathSpecific™ Ataxin-3/ATXN3 Deubiquitination Assay Kit-Fluorogenic (CAT#: ZL-0424-WR50)
| Overview | |
|---|---|
| Description | This kit is designed to measure Ataxin-3 activity for screening and profiling applications, in a homogeneous assay with no timeconsuming washing steps. |
| Features | Ready-used for deubiquitination assay |
| Applications | Useful for examining enzyme kinetics and HTS applications. |
| Assay Measures | Fluorogenic |
| Research Areas | Kinase Drug Discovery; Signal Pathway |
| Specification | |
|---|---|
| Size | 96 tests |
| Components | This kit includes purified Ataxin-3 protein, Ubiquitin-AMC, and Ataxin-3 assay buffer for 100 enzyme reactions. |
| Target | Ataxin-3/ATXN3 |
| Target/Description | The Human Ataxin-3 (ATX3 or ATXN3) protein, also known as Josephin (JOS) or Machado-Joseph disease protein 1 (MJD1), is associated with Machado-Joseph disease, a neurodegenerative disorder characterized by progressive cerebellar ataxia. Additionally, ATX3 has clinical significance in gastric, lung, and testicular cancers. |
| Format | Fluorometric assay kit. |
| Storage | Store at the appropriate temperature as directed. |
| Handling | Please handle the product at appropriate storage condition once received. |
| Shipping | Dry ice |
| Regulatory Status | RUO |
For Research Use Only.
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