PathSpecific™ EGF-R (T790M) Assay Kit (Luminescent) (CAT#: ZL-0524-WR23)
| Overview | |
|---|---|
| Description | This kit is designed to measure EGFR (T790M) Kinase activity for screening and profiling applications |
| Features | Ready-used for enzymatic activity assay. |
| Applications | Useful for examining enzyme kinetics and screening small molecule inhibitors for drug discovery in high throughput screening (HTS) applications. |
| Assay Measures | Luminescent |
| Research Areas | Kinase Drug Discovery; Signal Pathway; |
| Specification | |
|---|---|
| Size | 96 tests |
| Components | This kit includes enough purified recombinant EGFR(T790M) enzyme, EGFR substrate, ATP, and kinase assay buffer for 100 enzyme tests. |
| Target | EGFR(T790M) |
| Target/Description | EGFR(T790M) mutation is found as a second-site mutation in approximately 50% of EGFR-mutated lung tumors. This mutation confers resistance to many tyrosine kinase inhibitors, making the development of new targeted therapies essential in combating this form of drug resistance. |
| Format | Luminescent Assay Kit |
| Storage | Store at the appropriate temperature as directed. |
| Handling | Please handle the product at appropriate storage condition once received. |
| Shipping | Dry ice |
| Regulatory Status | RUO |
For Research Use Only.
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