PathSpecific™ EGFR (T790M, C797S) (del746-750) Assay Kit (Luminescent) (CAT#: ZL-0524-WR22)
| Overview | |
|---|---|
| Description | This kit is designed to measure the kinase activity of mutant EGFR (T790M, C797S) (del746-750) for screening and profiling applications. |
| Features | Ready-used for enzymatic activity assay. |
| Applications | Useful for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and high throughput (HTS) applications. |
| Assay Measures | Luminescent |
| Research Areas | Kinase Drug Discovery; Signal Pathway; |
| Specification | |
|---|---|
| Size | 96 tests |
| Components | This kit includes enough purified recombinant EGFR (T790M, C797S) (del746-750) kinase, kinase substrate, ATP, and kinase assay buffer for 100 enzyme tests. |
| Target | EGFR (T790M, C797S) (del746-750) |
| Target/Description | d746-750, T790M, and C797S mutations in EGFR can cause resistance to known EGFR inhibitors, requiring the development of next generation mutant-selective inhibitors. |
| Format | Luminescent Assay Kit |
| Storage | Store at the appropriate temperature as directed. |
| Handling | Please handle the product at appropriate storage condition once received. |
| Shipping | Dry ice |
| Regulatory Status | RUO |
For Research Use Only.
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