PathSpecific™ Factor XII/XIIa Assay Kit, Colorimetric (CAT#: ZL-1122-WR28)
| Overview | |
|---|---|
| Description | The kit is utilized for the quantitative assessment of Factor XIIa activity in biological samples such as plasma. |
| Features | Ready-used for quantative assay. |
| Applications | Kit is used to study the Factor XIIa protease in biological samples. |
| Application Notes | This kit provides an easy-to-use method for detecting Factor XIIa (as low as 1 mPEU) from plasma samples, also offering measurements for Factor XII. During the sample preparation, the Factor XII is converted to Factor XIIa by the FXII activator. |
| Molecular Mechanism of Action | The kit is designed to measure the amidolytic activity of factor XIIa by quantifying the release of p-Nitroaniline (pNA) through a colorimetric assay. The change in absorbance at 405 nm directly correlates with the enzymatic activity of factor XIIa. |
| Assay Measures | Colorimetric-based detection |
| Research Areas | Kinase Drug Discovery; Signal Pathway; |
| Specification | |
|---|---|
| Size | 100 tests |
| Components | The kit is supplied with an assay kit including FXIIa activator, FXIIa assay buffer, FXIIa inhibitor, FXIIa substrate, human Factor XIIa, human Factor XIIa supplement, and pNA standard (0.1 M). |
| Target | Factor XIIa |
| Format | Supplied with colorimetric assay kit. |
| Storage | Store at -20°C |
| Handling | Please store the kit according to the storage instructions in the kit's manual upon receipt. |
| Shipping | Ice packs |
| Regulatory Status | RUO |
For Research Use Only.
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