PathSpecific™ Human MCL-1 Assay Kit, TR-FRET (CAT#: ZL-0124-WR33)
| Overview | |
|---|---|
| Description | The kit is a rapid and sensitive assay for detecting the activity of MCL-1 inhibitor compounds. It allows for the quantitative measurement of MCL-1 binding to its ligand in a homogeneous 384 reaction format. |
| Features | Ready-used for inhibitors screening assay. |
| Applications | Kit is used to screen compound and study to measure compound binding to the target. |
| Application Notes | Excellent for screening small molecule inhibitors in pharmaceutical research and high-throughput screening. |
| Research Areas | Kinase Drug Discovery; Signal Pathway; |
| Specification | |
|---|---|
| Size | 384 tests |
| Components | The kit is supplied with an assay kit including enough recombinant MCL1, MCL1 peptide ligand, assay buffer, Anti-His Terbium-Labeled Donor, and Dye-labeled Streptavidin Acceptor for 384 reactions |
| Target | MCL1 |
| Target/Description | The Fluorescence Resonance Energy Transfer (FRET) assay is a wash-free method for high throughput screening. It involves incubating a sample with a terbium-labeled donor, a dye-labeled acceptor, MCL-1, peptide ligand, and an inhibitor for 2 hours. The fluorescence intensity is then measured using a fluorescence reader, providing valuable insights into MCL-1 activity. |
| Format | Supplied with a TR-FRET assay kit. |
| Storage | Store at the appropriate temperature as directed. |
| Handling | Please store the kit according to the storage instructions in the kit's manual upon receipt. |
| Shipping | Dry ice |
| Regulatory Status | RUO |
For Research Use Only.
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