PathSpecific™ MMP14 Assay Kit, Fluorogenic (CAT#: ZL-0124-WR23)
| Overview | |
|---|---|
| Description | This kit allows for the rapid and sensitive measurement of MMP14 activity in biological samples. It utilizes a homogeneous assay format that eliminates the need for time-consuming washing steps, making it convenient for high-throughput screening and profiling applications. |
| Features | Ready-used for enzyme activity assay. |
| Applications | Kit is used to study the MMP 14 protease in biological samples. |
| Application Notes | Excellent for investigating enzyme kinetics and applications in high throughput screening. |
| Research Areas | Kinase Drug Discovery; Signal Pathway; |
| Specification | |
|---|---|
| Size | 96 tests |
| Components | The kit is supplied with an assay kit including purified MMP14 enzyme, fluorogenic substrate, and MMP assay buffer for 100 enzyme reactions. |
| Target | MMP 14 |
| Target/Description | MMP14 (matrix metalloproteinase 14) is a protein that regulates the activity of various extracellular and plasma membrane proteins, influencing processes such as cell-cell and cell-extracellular matrix degradation and remodeling, cell invasion, and cancer metastasis. It is highly expressed in sarcomas and its levels correlate with breast cancer progression. Upregulation of MMP14 also promotes glioma invasion and tumor cell proliferation, and it plays a role in angiogenesis. |
| Format | Supplied with a fluorometric assay kit. |
| Storage | Store at the appropriate temperature as directed. |
| Handling | Please store the kit according to the storage instructions in the kit's manual upon receipt. |
| Shipping | Dry ice |
| Regulatory Status | RUO |
For Research Use Only.
Online Inquiry