| Overview | |
|---|---|
| Description | The kit offers a quick, easy, sensitive, and reliable method for testing MMP-3 activity, suitable for high throughput assays with an assay sensitivity under 50 µU. |
| Features | Ready-used for protease assay. |
| Applications | Kit is used to study the MMP 3 protease in biological samples. |
| Application Notes | MMP-3 specifically breaks down a FRET substrate, thus releasing the Mca fluorescent group, which can be measured fluorometrically at Ex/Em=325/393 nm. |
| Research Areas | Kinase Drug Discovery; Signal Pathway; |
| Specification | |
|---|---|
| Size | 100 tests |
| Components | The kit is supplied with an assay kit including Mca Standard (1mM), MMP-3 Assay Buffer, MMP-3 Positive Control (lyophilized), and MMP-3 Substrate. |
| Target | MMP 3 |
| Species Reactivity | Mammals, Other species |
| Target/Description | MMP-3 specifically activates gelatinase B, collagenases, and certain serpin-type serine proteinase inhibitors. It also releases various cell surface molecules, such as E-cadherin, which is associated with cancer development. |
| Sensitivity | 0.05 mU/well |
| Format | Supplied with a fluorometric assay kit. |
| Storage | Store at -20°C |
| Handling | Please store the kit according to the storage instructions in the kit's manual upon receipt. |
| Shipping | Dry ice |
| Regulatory Status | RUO |
For Research Use Only.
