PathSpecific™ Human PRMT5 Assay Kit, TR-FRET (CAT#: ZL-0224-WR18)
| Overview | |
|---|---|
| Description | This kit is devised to quantitatively analyze PRMT5 activity in a homogeneous 384 reaction setup. |
| Features | Ready-used for enzymatic activity assay |
| Applications | Kit is used for compound screening and profiling. |
| Application Notes | Excellent for exploring the kinetics of enzymes and HTS applications. |
| Research Areas | Kinase Drug Discovery; Signal Pathway; |
| Specification | |
|---|---|
| Size | 384 tests |
| Components | The kit is supplied with histone H4 peptide substrate, a Eu-labeled antibody, S-adenosylmethionine, methyltransferase assay buffer, FRET detection buffer, dye-labeled acceptor, and purified PRMT5. |
| Target | PRMT5 |
| Target/Description | PRMT5 is a histone methyltransferase that targets H4-R3 for methylation. The PRMT5 TR-FRET assay kit utilizes a FRET-based method that eliminates the need for lengthy washing steps, ideal for high throughput screening. The assay kit's specificity is attributed to an antibody designed to identify methylated substrates accurately. |
| Format | Supplied with a TR-FRET assay kit |
| Storage | Store at -80°C. |
| Handling | Please store the kit according to the storage instructions in the kit's manual upon receipt. |
| Shipping | Dry ice |
| Regulatory Status | RUO |
For Research Use Only.
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