| Overview | |
|---|---|
| Description | The kit is specifically designed for the detection and quantification of PRMT8 enzyme activity in biological samples for screening and profiling applications. |
| Features | Ready-used for enzymatic activity assay |
| Applications | Kit is used for compound screening and profiling. |
| Application Notes | Excellent for exploring the kinetics of enzymes and HTS applications. |
| Research Areas | Kinase Drug Discovery; Signal Pathway; |
| Specification | |
|---|---|
| Size | 96 tests |
| Components | The kit is supplied with a 96-well plate precoated with histone H4 peptide substrate, the antibody against methylated arginine 3 (R3) residue of Histone H4, the secondary HRP-labeled antibody, S-adenosylmethionine, methyltransferase assay buffer, and purified PRMT8 enzyme for 100 enzyme reactions. |
| Target | PRMT8 |
| Target/Description | The PRMT8 assay kit includes a specialized antibody that targets the methylated R3 residue of Histone H4 for accurate detection of methyltransferase activity. It involves a straightforward three-step process on a microtiter plate, starting with incubating the enzyme with the substrate, followed by the addition of primary antibody, and concluding with chemiluminescent measurement using an HRP-labeled secondary antibody and substrate. |
| Format | Supplied with a chemiluminescent assay kit |
| Storage | Store at the appropriate temparature as directed. |
| Handling | Please store the kit according to the storage instructions in the kit's manual upon receipt. |
| Shipping | Dry ice |
| Regulatory Status | RUO |
For Research Use Only.
