| Overview | |
|---|---|
| Short Name | PTPN11/SHP2 (E76K)-FL Phosphatase Assay |
| Assay Overview | Creative Biolabs provides several specific target assays for the investigation of test articles focus the specific pathway. Full-length PTPN11/SHP2 (E76K) Phosphatase Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity. The assay will be customized according to the client's specific requirements. Please contact our scientists for assay development and custom-tailored screening details. |
| Assay type | Fluorescence-based Assay |
| Assay Properties | |
|---|---|
| Short Description | Full-length PTPN11/SHP2 (E76K) Phosphatase Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity. |
| Substrates/Cell Line | Fluorogenic substrate DiFMUP, 100 μM With/without activating peptide [H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQK-amide] |
| Assay subtype | Enzymatic Activity Assay |
| Readout | Enzymatic activity |
| Assay format | 96-wells format |
| Target | |
|---|---|
| Target | PTPN11/SHP2 (E76K)-FL |
| Synonyms | Tyrosine-protein phosphatase non-receptor type 11; Protein-tyrosine phosphatase 1D; Protein-tyrosine phosphatase 2C; SH-PTP2; SH-PTP3; PTP2C; SHPTP2 |
| Target Species | Human |
| UniProt ID | Q06124 |
For Research Use Only.
