PathSpecific™ SARS-CoV-2 Mpro Assay Kit (CAT#: ZL-0124-WR46)
| Overview | |
|---|---|
| Description | This kit is a quick and user-friendly FRET-based assay that involves only two simple steps. First, the Mpro enzyme is combined with the compound and left to incubate for 30 minutes. Then, the substrate solution is added to initiate the reaction. The fluorescent intensity is easily determined using a fluorescent plate reader at specific excitation and emission wavelengths. |
| Features | Ready-used for inhibitors screening assay. |
| Applications | Kit is used to screen the Mpro Inhibitors. |
| Application Notes | Useful for screening of Mpro inhibitors. |
| Research Areas | Kinase Drug Discovery; Signal Pathway; |
| Specification | |
|---|---|
| Size | 1 EA |
| Components | The kit is supplied with an assay kit including 2X Protease Assay Buffer, 0.5 M DTT, 5 mM Substrate, Recombinant SARS-CoV-2 Mpro, and Black low binding 96 well plate. |
| Target | SARS-CoV-2 Mpro |
| Target/Description | Mpro of Severe acute respiratory Coronavirus 2 (SARS CoV-2 Mpro, also known as SARS-CoV-2 Main protease or SARS-CoV-2 3CL protease) is crucial for viral replication as it processes the polyproteins 1ab at 11 specific cleavage sites. Inhibiting the activity of this enzyme holds promise for developing effective anti-coronaviral therapeutic agents. |
| Format | Supplied with a FRET-based assay kit. |
| Storage | Store at the appropriate temperature as directed. |
| Handling | Please store the kit according to the storage instructions in the kit's manual upon receipt. |
| Shipping | Dry ice |
| Regulatory Status | RUO |
For Research Use Only.
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