| Overview | |
|---|---|
| Description | The kit is useful for evaluating the activity of SMYD3 (SET and MYND domain-containing protein 3) in screening and profiling studies. |
| Features | Ready-used for enzymatic activity assay |
| Applications | Kit is used for compound screening and profiling. |
| Application Notes | Excellent for exploring the kinetics of enzymes, screening small molecule inhibitors, and HTS applications. |
| Research Areas | Kinase Drug Discovery; Signal Pathway; |
| Specification | |
|---|---|
| Size | 384 tests |
| Components | The kit is supplied with enough purified recombinant SMYD3/HSP90 complex, GST-tagged SMYD3 substrate, primary antibody and methylation assay buffer for 384 enzyme reactions. |
| Target | SMYD3 |
| Target/Description | SMYD3, or SET and MYND domain-containing protein 3, is a member of the lysine methyltransferase family involved in methylation of histone substrates like H3K4 and H4K5. Additionally, it modifies non-histone proteins such as VEGFR1, MAP3K2, AKT1, and HER2. |
| Format | Supplied with a homogeneous assay kit |
| Storage | Store at the appropriate temparature as directed. |
| Handling | Please store the kit according to the storage instructions in the kit's manual upon receipt. |
| Shipping | Dry ice |
| Regulatory Status | RUO |
For Research Use Only.
