PI3K/AKT Pathway-FOXO Reporter Kit (CAT#: ZL-1123-WR6)

Overview
DescriptionThe kit contains a transfection-ready FOXO3 expression vector, FOXO luciferase reporter vector, and negative control vector. The reporter vector contains a firefly luciferase gene under the control of multimers of the FOXO-responsive element located upstream of a minimal promoter.
FeaturesReady-used for cell signaling pathway assay.
ApplicationsThe FOXO Reporter kit is designed to monitor activity of the PI3K/AKT signaling pathway and the transcriptional activity of FOXO proteins in cultured cells.
Application Notes• Monitor PI3K/Akt signaling pathway activity and FOXO transcriptional activity.
• Screen for PI3K/AKT signaling pathway compound activity.
• Study effects of RNAi or gene overexpression on the activity of the PI3K/AKT pathway.
Research AreasDrug Discovery; Immunology; Oncology
Specification
Size500 reactions
ComponentsReporter: FOXO luciferase reporter vector & Renilla luciferase vector
Negative Control Reporter: Non-inducible luciferase vector & Renilla luciferase vector
TargetPI3K/AKT
FormatSupplied with reporter vector group and negative control vector group.
StorageStore kit components at -20°C.
HandlingPlease place the product at proper storage condition once received.
ShippingIce packs
Regulatory StatusRUO

For Research Use Only.

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