TGFβ/SMAD Pathway-SBE Reporter Kit (CAT#: ZL-1123-WR20)

Overview
DescriptionThe kit contains a transfection-ready SBE luciferase reporter vector and a negative control vector. The reporter vector includes a firefly luciferase gene under the control of a multimerized SBE-responsive element located upstream of a minimal promoter.
FeaturesReady-used for cell signaling pathway assay.
ApplicationsKit is used to study the TGFβ/SMAD signaling pathway and SBE transcriptional activity in cultured cells.
Application Notes• Monitor TGFβ signaling pathway activity.
• Screen for activators or inhibitors of the TGFβ/ SMAD signaling pathway.
• Study effects of RNAi or gene overexpression on the activity of the TGFβ pathway.
Research AreasDrug Discovery; Immunology; Oncology
Specification
Size500 reactions
ComponentsReporter: SBE luciferase reporter vector & Renilla luciferase vector
Negative Control Reporter: Non-inducible luciferase vector & Renilla luciferase vector
TargetTGFβ/SMAD
FormatSupplied with reporter vector group and negative control vector group.
StorageStore kit components at -20°C.
HandlingPlease place the product at proper storage condition once received.
ShippingIce packs
Regulatory StatusRUO

For Research Use Only.

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