Wnt Pathway-TCF/LEF Reporter Kit (CAT#: ZL-1123-WR24)

Overview
DescriptionThe kit includes a transfection-ready TCF/LEF luciferase reporter vector and a negative control vector. The reporter vector includess a firefly luciferase gene under the control of a multimerized TCF/LEF responsive element located upstream of a minimal promoter
FeaturesReady-used for cell signaling pathway assay.
ApplicationsKit is used to study the Wnt signaling pathway and TCF/LEF transcriptional activity in cultured cells.
Application Notes• Monitor Wnt /β-catenin signaling pathway activity.
• Screen for activators or inhibitors of the Wnt /β-catenin signaling pathway.
• Study effects of RNAi or gene overexpression on the activity of the Wnt /β-catenin pathway.
Research AreasDrug Discovery; Immunology; Oncology
Specification
Size500 reactions
ComponentsReporter: TCF/LEF luciferase reporter vector & Renilla luciferase vector
Negative Control Reporter: Non-inducible luciferase vector & Renilla luciferase vector
TargetTCF/LEF
FormatSupplied with reporter vector group and negative control vector group.
StorageStore kit components at -20°C.
HandlingPlease place the product at proper storage condition once received.
ShippingIce packs
Regulatory StatusRUO

For Research Use Only.

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