LVTX-8, Antimicrobial Peptide (AMP) (CAT#: BMWJ-0826-WJ484)
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LVTX-8 is a peptide toxin, exacted from Lycosa vittata. LVTX-8 has potent anticancer and and anti-metastasis activities towards lung cancer with strong cytotoxicity. LVTX-8 significantly induces apoptosis and inhibits the proliferation, invasion and migration of lung cancer cells through P53 hypoxia pathways and integrin signaling. LVTX-8 significantly inhibits the tumor growth and metastasis in A549/H460 xenograft mice model.
| Overview | |
|---|---|
| Synonyms | LVTX-8; Lycosa vittata toxin 8 |
| Source | Snake/Reptile |
| Sequence | Ile-Trp-Leu-Thr-Ala-Leu-Lys-Phe-Leu-Gly-Lys-Asn-Leu-Gly-Lys-His-Leu-Ala-Lys-Gln-Gl n-Leu-Ser-Lys-Leu |
| Sequence Shortening | IWLTALKFLGKNLGKHLAKQQLSKL |
| Activity | Gram-positive bacteria; Gram-negative bacteria; Fungi; Virus; Cancer cells; Ion channel; Hemolytic |
| Physical State | Powder |
| Purity | >98% |
| Storage | The power can be stored at 4°C for 2 years or at -20°C for 3 years. |
For Research Use Only.
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