PathSpecific™ Total NAD and NADH Assay Kit-Colorimetric (CAT#: ZL-0725-WR13)
| Overview | |
|---|---|
| Description | Creative Biolabs' PathSpecific™ Total NAD and NADH Assay Kit-Colorimetric provides a convenient and sensitive method to detect NAD and NADH without purification. |
| Features | Convenient, sensitive, simple |
| Applications | To detect NAD and DADH in biological sample mix. |
| Assay Measures | Colorimetric |
| Research Areas | Cell metabolism assay; Drug discovery; |
| Absorbance | 570, 610 nm |
| Specification | |
|---|---|
| Size | 1 EA |
| Target | Total NAD and NADH |
| Target/Description | NAD+ is a crucial molecule with far-reaching roles beyond its well-known function in energy metabolism. Primarily, it acts as a redox carrier, accepting hydride ions from metabolic pathways like glycolysis and the TCA cycle to form NADH, which then fuels ATP synthesis through OXPHOS. However, NAD+ also serves as a vital co-substrate for a diverse array of enzymes, including sirtuins and PARPs, influencing processes like DNA repair, epigenetic modification, inflammation, and circadian rhythm. Furthermore, recent discoveries highlight its function as a nucleotide analog in DNA ligation and RNA capping. Consequently, dynamic changes in NAD+ levels, driven by cellular stress, significantly rewire biological processes through the post-synthesis modification of DNA, RNA, and proteins, with NAD+ deficiency linked to various diseases, including metabolic disorders, cancer, and neurodegeneration. |
| Alternative Names | Nicotinamide adenine dinucleotide; Coenzyme I; Diphosphopyridine nucleotide (DPN+); β-NAD; β-DPN; 1-(3-Carbamoylpyridinio)-β-D-ribofuranoside 5-(Adenosine-5'-pyrophosphate); Cozymase |
| Format | 400 Tests |
| Storage | Store at -20 °C, and protect from light. |
| Handling | Please place the product at proper storage condition once received. |
| Shipping | Ice bags |
| Regulatory Status | RUO |
For Research Use Only.
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