Polymyxin B1, Antimicrobial Peptide (AMP) (CAT#: BMWJ-0826-WJ1)
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Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment.
| Overview | |
|---|---|
| Synonyms | Polymyxin B1; PMB1 |
| Source | Bacteria |
| CAS | 4135-11-9 |
| Molecular Formula | C56H98N16O13 |
| Molecular Weight | 1203.48 |
| Sequence | {Dab(6-methyl-1-oxooctyl)}-Thr-{Dab}-{Dab}-{Dab}-{d-Phe}-Leu-{Dab}-{Dab}-Thr (Lact am bridge: Dab4-Thr10) |
| Sequence Shortening | {Dab(6-methyl-1-oxooctyl)}-T-{Dab}-{Dab}-{Dab}-{d-Phe}-L-{Dab}-{Dab}-T (Lactam bri dge: Dab4-Thr10) |
| Activity | Gram-negative bacteria; LPS; Biofilm; Cationic; Lipopeptide; Outer membrane |
| Physical State | Powder |
| Purity | >98% |
| Storage | The power can be stored at 4°C for 2 years or at -20°C for 3 years. |
For Research Use Only.
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