Protegrin-1, Antimicrobial Peptide (AMP) (CAT#: BMWJ-0826-WJ20)
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Protegrin-1 is an orally active antibacterial peptide. Protegrin-1 activates ERK, COX2, NFκB, inhibits Apoptosis, and NO production. Protegrin-1 has antibacterial activity against S. aureus, E. faecium, E. coli, P. aeruginosa and K. Pneumoniae, with MBC values between 10 and 20 µM. Protegrin-1 has antiviral activity against dengue NS2B-NS3. Protegrin-1 has anti-inflammatory activity. Protegrin-1 is used in the study of inflammatory diseases and infections.
| Overview | |
|---|---|
| Synonyms | PG1; Protegrin-1; PG-1; Protegrin I |
| Source | Porcine |
| CAS | 168831-77-4 |
| Molecular Formula | C88H147N37O19S4 |
| Molecular Weight | 2155.61 |
| Sequence | Arg-Gly-Gly-Arg-Leu-Cys-Tyr-Cys-Arg-Arg-Arg-Phe-Cys-Val-Cys-Val-Gly-Arg-NH2 (Disulf ide bridge:Cys6-Cys15;Cys8-Cys13) |
| Sequence Shortening | RGGRLCYCRRRFCVCVGR-NH2 (Disulfide bridge:Cys6-Cys15;Cys8-Cys13) |
| Activity | Gram-positive bacteria; Gram-negative bacteria; Fungi; Virus; HIV; Cancer; Biofilm; STD; Porcine; Cathelicidin |
| Physical State | Powder |
| Purity | >98% |
| Storage | The power can be stored at 4°C for 2 years or at -20°C for 3 years. |
For Research Use Only.
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