| Overview | |
|---|---|
| Description | Creative Biolabs offers a wide range of dye reagents and kits suitable for evaluating cell biological activity such as apoptosis, endocytosis and can be used in a number of areas: drug discovery, toxicity testing and immunology. Apoptosis Detection Reagent, Annexin V-PE Conjugation-S is used for identification and enumeration of dead cells, such as apoptotic or necrotic cells, by FC, IF. |
| Features | Convenient, and simple steps; Be compatible with various antibody function study platforms; Reduced signal variability and improved timing in sensitive experiments; |
| Applications | Be used for the identification and enumeration of dead cells, such as apoptotic or necrotic cells, by flow cytometry. |
| Molecular Mechanism of Action | In most normal, viable eukaryotic cells, the negatively charged phospholipid PS is located in the cytosolic leaflet of the plasma membrane lipid bilayer. During apoptosis, PS redistribution from the inner to the outer leaflet.The Annexin V conjugates selectively label apoptotic, necrotic, and dead cells through the specific binding of Annexin V to phosphotidylserine (PS). |
| Assay Measures | Fluorescence |
| Research Areas | Drug Discovery and Toxicity Testing; Immunology |
| Specification | |
|---|---|
| Size | 30 Tests |
| Storage | Store protected from light at 2-8 °C. Do not freeze. |
| Handling | Please place the product at proper storage condition once received. |
| Shipping | Ice packs |
For Research Use Only.
